Technical parameters: Model Number: GST-BC001 Power supply: 380VAC, 50/60Hz, 2/3 phase. Power: 1.5kw Working speed: 150-200pcs/min Machine weight: 5000kg Air source: 5-6kgf/cm². Overall Dimen
Technical parameters:
Model Number: GST-BC001
Power supply: 380VAC, 50/60Hz, 2/3 phase.
Power: 1.5kw
Working speed: 150-200pcs/min
Machine weight: 5000kg
Air source: 5-6kgf/cm².
Overall Dimension: L6800*W1400*H1800mm
Customized Support: Yes
The Guanshengtai Syringe Automatic Filling Machine is an integrated automated device designed specifically for the quantitative filling and sealing of pre-filled syringes. The equipment integrates automatic unpacking/loading, precision quantitative filling, nitrogen purging protection, and capping/sealing. It employs a high-precision stainless steel metering pump and servo drive system, ensuring filling accuracy within ±0.5%. Single-syringe filling volumes range from 0.5ml to 50ml, meeting the precise filling needs of various biological agents, medical aesthetic products, and sterile liquids.
Core Advantages:
High-Precision Filling System: Utilizing a servo motor-driven ceramic pump or stainless steel plunger pump, the filling volume is double-checked via a servo motor encoder and mechanical hard limit, eliminating pulse fluctuations and ensuring highly consistent drug volume in each syringe, resulting in excellent batch repeatability.
Bubble-Free Filling Technology: Utilizing a needle insertion filling method, the filling needle extends to the bottom of the syringe barrel, injecting while rising. This effectively avoids air bubbles generated by liquid flow impact, ensuring a foam-free and cavitation-free liquid surface after filling. It is particularly suitable for biologics and vaccines sensitive to air bubbles.
Fully Automated Stoppering and Sealing: Equipped with a vacuum adsorption stoppering system, the rubber stopper is vertically pressed into the syringe barrel opening via a guide mechanism. Stopper placement accuracy is ≥99.9%, ensuring excellent sealing without misalignment, tipping, or incomplete sealing. This ensures the integrity of the sterile barrier during product transportation and storage.
Optional Nitrogen Purging Protection: For oxygen-sensitive products, a nitrogen purging device can be configured. Before filling, the syringe barrel cavity is purged with nitrogen, effectively reducing headspace residual oxygen and extending product shelf life. This is particularly suitable for high-end formulations such as vaccines, biological antibodies, and hyaluronic acid.
Optional Nitrogen Purging Protection: For oxygen-sensitive products, a nitrogen purging device can be configured. Nitrogen gas is used to purge and replace the oxygen in the headspace before filling, effectively reducing residual oxygen and extending product shelf life. This is especially suitable for high-end formulations such as vaccines, biological antibodies, and hyaluronic acid.
Cleanroom-Grade Design: The entire machine utilizes a SUS304 stainless steel frame and a transparent protective cover. The filling area meets Class 100 cleanroom requirements, allowing operation in aseptic workshops or under laminar flow hoods. It supports ozone/UV disinfection and fully complies with GMP and FDA aseptic filling standards.
Multi-Specification Quick Switching: Contact components such as the filling nozzle, feed tube, and piston seal are all quick-release structures, allowing for tool-free size changes or cleaning. By changing the specifications, it can quickly adapt to the filling needs of different syringe sizes, including 0.5ml, 1ml, 2ml, 5ml, 10ml, 20ml, and 50ml, with changeover time controlled within 30 minutes.
Multiple Safety Protections: Equipped with a multi-sensor protection system including tube shortage detection, no-tube-no-fill, and compartment blockage/insufficient-material alarms. In case of abnormalities, the machine automatically shuts down and provides audible and visual alerts, effectively preventing empty filling, leaks, and equipment damage.
Applicable Scenarios:
Widely applicable to the precise filling and packaging of sterile liquids in biopharmaceuticals (vaccine pre-filled solutions, monoclonal antibody injections, growth hormones, insulin), medical aesthetics (hyaluronic acid, collagen, facial fillers), ophthalmic drugs (sodium hyaluronate eye drops pre-filled solutions), and veterinary medicine (pet dewormers, vaccine syringes). Guanshengtai's automatic syringe filling machine, with its superior performance in high precision, high cleanliness, and high stability, helps pharmaceutical and medical aesthetic companies achieve standardized and large-scale production of pre-filled syringe products.
